Interview with Renato Dulbecco

Abstract

Interview in 1998 with Italian-American virologist Renato Dulbecco, who came to Caltech in 1949 as a senior research fellow at the invitation of Max Delbrück, joined the faculty of the Biology Division, and remained at Caltech until 1962. In this interview, he recalls his education at the University of Turin (MD 1936) in his native Italy, working with Giuseppe Levi and Rita Levi-Montalcini; his experiences during the war years in Italy; his arrival in the United States in 1947 to work with Salvador Luria on phage at Indiana University, where James Watson was a colleague; his meeting with Delbrück at Cold Spring Harbor; and his arrival at Caltech and eventual switch to the study of animal viruses. Discusses his work with western equine encephalitis virus, polio virus, Rous sarcoma virus, and his collaborations with postdoc Harry Rubin and student Howard Temin. Leaves Caltech in 1962 to join Michael Stoker at Glasgow University for a year, thence to Salk Institute for Biological Research, in La Jolla. Moves in 1972 to Imperial Cancer Research Fund Laboratories in London and works with Yoshi Ito. Focuses on breast cancer. Receives Nobel Prize in 1975 (with Howard Temin and David Baltimore). Returns to Salk in 1977. Recollections of Jonas Salk, David Baltimore, and Jacob Bronowski. In 1988, he succeeds Fred De Hoffmann as president of Salk. Resigns in 1992 and divides his time between La Jolla and the Milan laboratory of Italy's National Research Council, working on breast cancer.